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P Benefit from Treatment Strategy Cost treatment [in QALYS} Do nothing $0.00 0 $130,000.00 0.8 $10,000.00 1.0 0 $90,000.00 2.2 E $130,000.00 2.4 F 51

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P\" Benefit from Treatment Strategy Cost treatment [in QALYS} Do nothing $0.00 0 $130,000.00 0.8 $10,000.00 1.0 0 $90,000.00 2.2 E $130,000.00 2.4 F 51 30,000.00 3.2 $60,000.00 3.2 51?0,000.00 3.8 $130,000.00 4.0 $110,000.00 4.0 Plot the eleven treatment strategies [he sure to include "do nothing"} on graph paper. Make sure you choose a scale that allows all eleven strategies to fit. Draw the CostEffectiveness Frontier for these treatment options. {Hint: the cost iprice}_goes on the x axis and effectiveness, which we measure here in QALYs goes on the '1' axis.[ What treatment strategies are on the Cost Effectiveness Frontier? Why do these strategies fa|| on the frontier {what characteristics do these strategies share]? Which treatment strategies are the dominated treatment strategies? Why? For this question, assume that Treatment Strategy G has been withdrawn from the market because of a newly discovered safety problem. How does this change the relative cost- effectiveness of the remaining strategies? How does the cost-effectiveness frontier change? List the dominant strategies and the dominated treatments. For this question, include the assumption you made in question 5, and make the additional assumption that the patent covering Treatment Strategy H has expired. Generic pharmaceutical companies offer to sell a generic version of Treatment Strategy H at onehalf its previous price. Does this change the costeffectiveness frontier? Which treatments now lie on the costeffectiveness frontier and which are the dominated treatment strategies? Define QALY. DCI NUT SURF THE lWEB to get this answer. Define ICER. What is the formula for calculating the lCER of two treatment strategies, X and 'f. Identify gL|_o_f_ the variables in the formula. DO NOT SURF THE WEB- to get this answer. Calculate the Incremental Cost Effectiveness Ratio {ICER} for Treatment Strategy G compared with Treatment Strategy D [assume no health insurance}. Show your work In your own words, explain how an individual suffering from econosomiasis would use the NIH to decide whether to take Treatment Strategy G over receiving no treatment. Define the value of a statistical life (VSL) in your own words and describe one way in which researchers have tried to estimate the VSLI

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