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Part (C) [30 Marks] Based on the following structures and activities for captopril and its analogues, propose the structure of the pharmacophore of captopril. HS

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Part (C) [30 Marks] Based on the following structures and activities for captopril and its analogues, propose the structure of the pharmacophore of captopril. HS , O Captopril ya walowe H HS HS HS HO , COH , O relative Ki 120 relative Ki 1,100 relative Ki 12,500 relative Ki 12 wyr whom wa HS N HS HS N , , OH relative Ki 10 relative Ki 12,000 relative Ki 650

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