The Lentiviral vector is derived from the HIV virus but is modified to be safe for gene therapy in humans. Which of the following
The Lentiviral vector is derived from the HIV virus but is modified to be safe for gene therapy in humans. Which of the following statements best describes the modifications to the viral genome of the Lentiviral vector that is used to infect host cells from the patient for gene therapy? Choose one. Select an answer and submit. For keyboard navigation, use the up/down arrow keys to select an answer. a b The Lentiviral vector genome is (+)RNA that encodes the therapy transgene with regulatory sequences for its expression and LTR sequences that are needed for reverse transcription of the RNA genome and for integration of the resulting dsDNA vector DNA into the host chromosome. The Lentiviral vector genome is (+)RNA that encodes the therapy transgene and the pol gene for reverse transcriptase and integrase with regulatory sequences for their expression and LTR sequences that are needed for reverse transcription of the lentiviral vector genome and its integration into the host genome.. The Lentiviral vector genome is (+)RNA that encodes the therapy transgene and all the genes required for reverse transcription/integration of the viral genome (pol) and virus replication (gag & env), but the virulence factors of HIV are deleted. X Your answer
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