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Pioglitazone is a drug that is prescribed to treat diabetes. Its mechanism of action is to disrupt the interactions between some of the membrane-embedded portions

Pioglitazone is a drug that is prescribed to treat diabetes. Its mechanism of action is to disrupt the interactions between some of the membrane-embedded portions of Complex I and the rest of the Complex. Explain the effect of pioglitazone on electron transport and ATP synthesis. Why do you think pioglitazone is used to treat diabetes?

 

 

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