Please help. Answer all the questions and be original. A contractor must provide a Textile unit with 10,000 paper cones per day. When he begins a production run, he discovers that he can produce 25,000 sheets of paper per day. For one year, the cost of keeping a cone in stock is 2 paise, and the cost of setting up a production run is Rs.18. The factory's annual working days are 300.

Q1.

Can you suggest possible causes for a 55-year-old female waking regularly at midnight three to four times a month, feeling that she is going to die and feeling an urge to meet people at that time. She has no breathlessness.

Q2. What is the modern treatment and prognosis for manic depressive disorder? Is there a malfunction of a metabolic pathway that causes it? Can it be remedied by treatment with neurotransmitter-stimulating drugs? If so which drugs are the most effective apart from lithium carbonate and carbamazepine?

Q3.

Is lamotrigine as effective a mood stabilizer as lithium?

Q4.

Is it safe to prescribe lithium for a patient with bipolar mood disorder with biliary cirrhosis and 40% blockage of the main coronary system?

Q5.

How long should the period of active and maintenance treatment last with mood stabilizers in a patient presenting with his first manic episode?

Q6.

Do lithium and selective serotonin re-uptake inhibitors (SSRIs) have an anti-impulse effect?

Q7.

Can any of the antipsychotics clozapine, olanzepine and quetiapine be used as mood stabilizers in bipolar affective disorder?

Q8.

Is hypothyroidism secondary to chronic lithium therapy in the treatment of bipolar affective disorder, reversible on discontinuation of lithium or its substitution by another mood stabilizer?

Q9.

In bipolar affective disorder in patients who are well controlled on lithium, is it possible to prescribe thiazide diuretics when hypertension is difficult to control?

Q10.

Are antipsychotics recommended as the most effective treatment for trichotillomania?