please help, thanks much

RESEARCH ARTICLE REVIEW PROBLEMS

1) Using the article labeled "Transfer Anxiety MI" answer the following questions.

(8 pts.)

1. The baseline anxiety and information scores were not significantly different between the experimental and comparison groups.What does this mean? Does this strengthen or weaken the results of the study?Provide a rationale for your answer.
2. The results indicated a statistically significant difference between the anxiety score for the two groups of patients (t=3.875, p<.0001). What do these results mean?
3. The results indicated a statistically significant difference between the anxiety scores for the two groups of patients (t = 3.875, p < .0001). Are these results also significant at the .01 level? Provide a rationale for your answer.
4. How might you use these study findings in practice?

ADDITIONAL PROBLEMS

Problems 1 - 4 deal with comparing two population means using independent and dependent samples.

1 - Preeclampsia and Gestational Age

(this example is worked through in the narrated Powerpoint, see if you can reproduce the results)

The goal of study conducted by Baker et. al. was to determine whether medical deformation alters in vitro effects of plasma from patients with preeclampsia on endothelial cell function to produce a paradigm similar to in vivo disease state. Subjects were 24 nulliparous pregnant women before delivery, of whom 12 had preeclampsia and 12 were normal pregnant patients. The patients were independently sampled from these populations and were not matched according to any criteria. Among the data collected were the gestational ages (in weeks) at delivery.

Research Question: Is there evidence to suggest that the mean gestational age at delivery for mothers with preeclampsia is lower than that for mothers with a normal pregnancy?

Use JMP to analyze these data. You can enter the data in JMP yourself. You will need two columns, one to denote the group and the other to contain the response, in this case gestational age at birth. Be sure to check assumptions and perform your analysis accordingly.

Data:

Preeclampsia: 38, 32, 42, 30, 38, 35, 32, 38, 39, 29, 29, 32 Normal: 40, 41, 38, 40, 40, 39, 39, 41, 41, 40, 40, 40

a) Perform a hypothesis test answer the question of interest and summarize your findings. (4 pts.) b) Find and report the 95% CI for the difference in the population means from the JMP output. Discuss this interval in practical terms. (2 pts.)

4 - Middle Ear Effusion in Breast-Fed and Bottle-Fed Infants A common symptom of otitus media in young children in the prolonged presence of fluid in the middle ear, known a middle-ear effusion. The presence of fluid may result in temporary hearing loss and interfere with normal learning skills in the first two years of life.One hypothesis is that babies who are breast-fed for at least 1 month build up some immunity against the effects of the disease and have less prolonged effusion than do bottle-fed babies.A small study of 24 pairs of babies is set up, where the babies are matched on a one-to-one basis according to age, sex, socioeconomic status, and type of medications taken. One member of the matched pair is a breast-fed baby, and other member is a bottle fed baby. The outcome variable is the duration of middle-ear effusion (in days) after the first episode of otitus media. The results are shown below.

Pair Number	Duration of effusion in breast-fed baby	Duration of effusion in bottle-fed baby	Difference
1	20	18
2	11	35
3	3	7
4	24	182
5	7	7
6	28	33
7	58	223
8	39	57
9	17	76
10	17	186
11	12	29
12	52	39
13	14	15
14	12	21
15	30	28
16	7	8
17	15	27
18	65	77
19	10	12
20	7	8
21	19	16
22	34	28
23	25	20

Do these data provide evidence that breast-fed babies have shorter durations of effusion when compared to bottle-fed babies that are the same age, sex, socioeconomic status, and on the same medications? Enter these data into JMP and conduct the appropriate analysis. (6 pts.)