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Problem I: Michaclis-Menton enzyme kinetics The Michaelis-Menten equation is a model of enzyme kinetics. During an enzyme-catalyzed reaction, the substrate (S) binds to the enzyme

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Problem I: Michaclis-Menton enzyme kinetics The Michaelis-Menten equation is a model of enzyme kinetics. During an enzyme-catalyzed reaction, the substrate (S) binds to the enzyme (E) to form the enzyme-substrate complex (ES). While it is part of this complex, the substrate is converted to product; in other words, the enzyme-substrate complex is converted to an enzyme-product complex (EP). This then dissociates to enzyme and free product (P). E+S ES EP E + P The rate of the reaction (v) is the rate of appearance of P. This rate is known to depend upon the concentration of S (IS]) in the reaction. The Michaelis-Menten model describes the relationship between v and [S]: where v is the reaction rate, Vmas is the maximum reaction rate (the value of v when all of the E has been converted to ES, at saturation). [S] is the substrate concentration, and Kmis the Michaelis-Menten constant, which is a measure of the tightness of binding of E to S Write a MATLAB program which calculates v as a function of [S]. Set [S] within the range 0-80 mM, and Vmax as 0.10 mM/min. Plot v as a function of [S], for three different values of Km: Km-5 mM, Km=10 mM, Km=20 mM. Your plot should have three curves, appropriate axes labels and a legend. (Don't forget the units of v.) . You shouldn't run the program 3 times to do this. . Do not write out the equation for v 3 times! The most efficient method is to create an array for reaction velocity (v), in which each column contains the values of v (vs. S) for a different value of Km. You can then plot the array v vs. S in one plot statement

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