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Q slingshot bookstore - Search * @ Slingshot - Slingshot Account St x @ Indiana Wesleyan University Can x _ Managerial Epidemiology X + X C 8 https://platform.virdocs.com/r/s/0/doc/1586119/sp/235448747/mi/695800755?cfi=%2F4%2F2%2F42%2F2%20%2F1%3A0%20%2F1%3A0 {3 SE . . Welcome to RedShelf eReader! X Just getting started? Head over to our partner support page for a guide on the basics. on54 The sensitivity of the capillary blood glucose (CBG) test for men with and without hypertension is 93.8 percent and the specificity is 90.5 percent. Among women v- - E 469 ypertension, the sensitivity of the CBG test is 74 percent and the specificity is 97.3 percent. + - D ooo Questions 22. Assume a population of 100,000 each of men and women with and without hypertension. Use exhibit H.5 as a template to calculate the number of men and women in this age group with and without hypertension who will have diabetes but test negative (false negatives) 23. Why are there nearly four times as many false negative women with and without hypertension? 24. How many false positive men and women with and without hypertension are there? O 25. Why are there more than three times as many false positive men than women with and without hypertension? EXHIBIT H.5 CBG Test Characteristics, 45-Year-Old Men and Women p. 469 HBP Men DM+ DM- HBP Women DM+ DM- CBG+ CBG+ + CBG- CBG- Totals 100,000 Totals 100,000 LBP Men LBP Women CBG+ CBG+ CBG- CBG- Totals 100,000 Totals 100,000 Notes: HBP = with hypertension; LBP = without hypertension. The authors report total lifetime costs of $4,917 for those who received targeted screening at age 35 ($4,551 without screening), $3,820 at age 45 ($3,415 without screening), $4,292 at age 55 ($3,682 without screening), $1,242 at age 65 ($998 without screening), and $952 at age 75 ($720 without screening). Incremental QALYs are reported to be 0.004, 0.008, 0.018, 0.008, and 0.007, respectively, for the five age groups. The authors report total lifetime costs of $4,700 for those with universal screening at age 35 ($4,369 without screening), $3,627 at age 45 ($3,263 without screening), $3,351 at age 55 ($2,872 without screening), $1,007 at age 65 ($805 without screening), and $374 at age 75 ($282 without screening). Incremental QALYs for universal screening are reported to be 0.003, 0.003, 0.008, 0.003, and 0.002, respectively, for the five age groups. Questions 26. For each screening strategy, use exhibit H.6 to calculate the incremental cost associated and the ICER for each age group. 27. How do the ICERs of targeted and universal screening compare across screening ages? O EXHIBIT H.6

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