Question 1 1 pts Suppose you were one of the researchers helping to establish that asbestos caused mesothelioma. Which ONE of the following study designs, ignoring any other considerations, would best help establish a causal relationship between asbestos exposure and mesothelioma? O A randomized control trial, where some participants are randomly selected to be exposed to asbestos and others are exposed to a harmless placebo. O A case-control study where participants with and without mesothelioma are recruited and then asked about their history of exposure to asbestos. O A prospective cohort study, where people who have been exposed asbestos and people who haven't are recruited to join a study and then whether or not they get mesothelioma in the future is observed. O A cross-sectional study where people are asked a) if there were ever exposed to asbestos, and b) if they have ever been diagnosed with mesothelioma. Question 2 1 pts Suppose you were one of the researchers helping to establish that asbestos caused mesothelioma. Which of the following study designs would allow you to comment on whether or not there was an association between asbestos exposure and mesothelioma AND be approved by an ethics committee? Select all that apply. O A randomized control trial, where some participants are randomly assigned to be exposed to asbestos and others are exposed to a harmless placebo. A case-control study where participants with and without mesothelioma are recruited and then asked about their history of exposure to asbestos. O A prospective cohort study, where people who have been exposed asbestos and people who haven't are recruited to join a study and then whether or not they get mesothelioma in the future is observed. ( A cross-sectional study where people are asked a) if there were ever exposed to asbestos, and b) if they have ever been diagnosed with mesothelioma.Question 3 1 pts Suppose you have just conducted an observational study to better understand the relationship between asbestos exposure and mesothelioma. Which following statements are TRUE? Select all that apply O If several well designed observational studies which were analyzed in a manner that thoroughly considered potential confounding and carefully attempted to correct for it in their analyses all found that exposure to asbestos was linked to mesothelioma, then this would suggest the likely possibility of a truly causal relationship. O If you saw higher levels of mesothelioma among those with higher levels of exposure then that is an indication of an association between asbestos and meothelioma. () If you randomly selected 50 people with mesothelioma and 50 people without mesothelioma and assess whether or not they were exposed to asbestos, and you see a strong association between the two, we can infer a causal relationship here. O No matter how well designed your observational study is, you may still have confounding variables you could not measure. O If there is evidence of a strong association, we can say our study confirms that exposure to asbestos causes mesothelioma. Question 4 1 pts A 2016 study showed that heavy alcohol consumption in adolescence is associated with lower IQ. Of the following, which TWO would be the most sensible confounders to worry about for this study? O Height O Family environment Alcohol consumption O Marijuana, tobacco and other substance use O IQ score Question 5 1 pts Which of the following best describes appropriate 'informed consent' in a research project involving people? Participants are informed about the findings of the research at the end of the project. O Participants are given a clear indication of what the research is about and what their involvement would entail. O Participants are informed about the different null and alternative hypotheses that will be performed in the study. Participants are told that the researcher is an expert in this area of study. O An institutional ethics committee is informed about the research project and the researcher(s) (as well as their academic background(s))