Question 1 Is there any role for heparin in management of septic shock? Question 2 Is there more adrenaline (epinephrine) or noradrenaline (norepinephrine) produced in shock? From where do these substances come from? Question 3 I hear conflicting views as to whether activated protein C is useful in shock. Question 4 Why does both vasoconstriction and vasodilatation occur in shock? Question 5 Are pulmonary artery (PA) catheters dangerous? Question 6 In most hospitals, what is the difference between a high-dependency unit (HDU) and an intensive care unit (ITU) and what is 'step down' care? Question 7 What is the difference between acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) from a practical point of view? Question 8 What is the role of inhaled nitric oxide (NO) in acute respiratory distress syndrome (ARDS)?