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QUESTION 1 Olestra is a fat substitute approved by the FDA for use in snack foods. Because there have been anecdotal reports of gastrointestinal
QUESTION 1 Olestra is a fat substitute approved by the FDA for use in snack foods. Because there have been anecdotal reports of gastrointestinal problems associated with olestra consumption, a randomized, double-blind, placebo-controlled experiment was carried out to compare olestra potato chips to regular potato chips with respect to GI symptoms ("Gastrointestinal Symptoms Following Consumption of Olestra or Regular Triglyceride Potato Chips," J. of the Amer. Med. Assoc., 1998: 150152). Among 529 individuals in the control group (no olestra), 17.6% experienced an adverse GI event, whereas among the 563 individuals in the olestra treatment group, 15.8% experienced such an event. Compute a 98% confidence interval for the difference between the two true proportions.
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