Question 1

Read the following paper, and answer the questions below:

"Scott H., Biello SM., Woods HC. Radzeviciene L. Ostrauskas R. Egg consumption and the risk of type 2 diabetes mellitus: a case-control study. Public Health Nutrition, 2012;15(8): 1437-1441"

https://doi.org/10.1017/S1368980012000614

NOTE- PLEASE OPEN THE ABOVE ARTICLE USING this website-https://doi.org/10.1017/S1368980012000614

AND DO THE QUESTION. TABLE FOR CALCULATION IS PROVIDED IN THE ARTICLE

QUESTIONS

(a) "What justification/s do the authors provide for conducting this study. Please use bullet points and be concise."

(b) "What study design was used in this research, identify from the paper methods sectionskey characteristics that support the design you just noted.

Please use bullet points for each characteristic"

(c) "What is/are the main exposure/s and what is/are main outcome/ of this study in operational terms, that mean how the exposure/s were defined and how the outcome/s were defined? (this is usually clear in tables presentation and the methods section)"

(d) "What was the prevalence of first- degree family history of diabetes in cases and control and what was the prevalence of Obesity (BMI 30). Can these variables potentially confound the association between egg consumption and type 2 diabetes? Justify you answer"

(e) "build a 2 by 2 table in order to compute the crude associations (OR) between diabetes Type 2 and exposure to eggs; the exposure is low consumption (<1egg>

(f) "Was the crude OR you found above (in section e) differs from the Adjusted OR reported in this Table 2? Please explain your answer in no more than 100 words"

(note: the authors used symbols in the column headings of Table 2 to refer to the table legend at the bottom where they specify what are the variables that were used in their analyses to adjust the OR - first analysis they used Asterix (OR*) and in the additional analysis the author used the symbol ( ) where more variables were added to the analysis.

(g) "In the method section the authors reported what information they have collected. What could be source of random measurement error in this study and what can be prone to systematic error? did the authors refer in their discussion to measurement error ? "

(h) "Do you think there is a risk of selection bias in this study? Explain why yes or why not - this should not take more than 60 words?"

i) "What improvement to the study design or methodology you will suggest. It is enough to mention one improvement and explain with not more than 100 words why it will improve the study "