Question 1

You want to determine if a specific training program improves marathon times. You recruit 20 athletes with personal best marathon finishing times of ~2:55:00. Half undergo the training program, and half maintain their normal training regimens. After completing the training program, the athletes participate in a marathon race, and you compare their finishing times. This is an example of a(n) _____________ design.

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Unpaired

Question 2

You want to determine if smoking causes a specific type of lung cancer. You recruit 30 smokers, as well as 30 non-smokers who are individually matched with a smoker so that the rest of their anthropometric measures (height, weight, sex, etc.) are as similar as possible. You follow these individuals over 30 years and record the incidence of lung cancer in both groups over that time. This is an example of a(n) _______________ design.

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Question 3

You purchase 60 mice and collect bone marrow stem cells from each mouse. You assign stem cells from 20 mice to one of three doses of an experimental drug. You measure proliferation of these cells after 6 hours and compare the dose response. This is an example of a(n) ___________ design.

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Question 4

You want to determine if a specific training program improves marathon times. You recruit 20 athletes, making sure to match personal best times between sets of two subjects. Half undergo the training program, and the other half (matched to the intervention group) maintain their normal training regimens. After completing the training program, the athletes participate in a marathon race, and you compare their finishing times. This is an example of a(n) _____________ design.

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Paired

Unpaired

Question 5

You want to determine if a dietary intervention influences weight. You recruit 60 subjects and assign them to the dietary intervention. You measure body weight before and after the intervention and compare the two mean values to determine if they are different. This is an example of a(n) _____________ design.

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Paired

Unpaired