QUESTION 11

1. A clinical trial is being conducted in order to determine the efficacy of a new drug used to treat Rheumatoid arthritis. The efficacy of the medication will not only be determined by the physical improvement of symptoms but also by using a blood test to examine the concentration C-reactive protein (an inflammatory marker) in an individual's blood. If the researcher wants a margin of error for the level of C-reactive protein to be less than or equal to 3.0 mg/dL, and if the standard deviation for C-reactive protein concentrations among arthritis patients was previously documented at 8 mg/dL, how many patients should be recruited for each group in the study assuming a 95% confidence interval will be used to quantify the mean differences between the control group and the treatment group?

1. n for the treatment group = 112;nfor the control group = 111

2. n for the treatment group = 56;nfor the control group = 57

3. n for the treatment group = 55;nfor the control group = 55

4 n for the treatment group = 112;nfor the control group = 112