Question 1(18 marks; 3 marks for each part):Among many friends you have at least one friend who regularly boasts and makes false health claims on Instagram. Their recent claim was yoga helps in losing excessive body weight. When you ask for credible evidence you are responded with 'ghosting' and 'unfriending'. You do your own search through credible databases for available evidence but unfortunately you don't find any. After some reflection plan to conduct your own research study to explore the link between yoga and weight loss. As good practice, you give a serious thought to six main study designs (which you learned in EPID1000 few years ago which also reminded you of your gradual de-sensitization to the fear of numbers and statistics). You consider various study design options and what each would involve. For example, how you will carry out the study, what sort of study participants you will need for each design, what information needs to be collected to investigate the link, what measure of association/effect can be obtained for this purpose from each design, what could be one possible practical issue/or potential bias and one confounder or confounding factor that could affect your study and the findings. You will briefly describe these aspects as one paragraph for each design following the formatting instructions provided below.There will be no mark for repeating the same issue/bias and confounding factor for every study design.You can use the review exercise (tutorial 11) as a general guide but address only those aspects that are raised in the paragraph above. Please also re-visit the weekly epidemiology ilectures on study designs.

1. Cross-sectional study
2. Case Control study
3. Prospective Cohort study.
4. Retrospective Cohort study.
5. Quasi-experimental study.
6. Randomized controlled trial

Q1 Note 1: Please be specific. No marks will be given for writing general design features from the ilectures. We want you to 'apply' your knowledge of study designs in light of the given scenario. Write in direct language e.g. I will carry out this study by.........

Question 2(5 marks)

Write null and a non-directional alternative hypotheses that can be tested with an Independent Samples t test. Provide a short description of your findings. You will provide assessment of statistical significance for ALL questions. For this question please also include your assessment and interpretation of practical significance of findings. You will need to provide the manual working out using 'average SD' as denominator.