Question $24$

Under which conditions, the principal investigator $($PI$)$ can unblind the treatment of a patient

A$.$ opening the code can be done as soon as the patient is off study

B$.$ after three months under treatment, the patient wants to know what treatment he has received

C$.$ in case of emergency in which the knowledge of the treatment is deemed essential by the PI for the best interest of the patient$$s care

D$.$ the amount of severe adverse events yield to treatment discontinuation

E$.$ None of the above