Question 3 (1 point) One of the objectives of a 2005 study on thermogenin (or Ucp1) was to determine the reaction of its transcriptional synergy and regulation to the messenger RNA (mRNA) levels of Peroxisome Proliferator-Activated Receptor alpha (or PPAR alpha). During the experiment, the researchers exposed some of their backcross mice to 5C-cold environment and fed them under a high-fat diet for 7 days. Their Ucp1 and PPAR alpha levels after the research are provided in the plot below. What statement best describes the plot provided below. [Sources: Xue, B., Coulter, A., Rim, J. S., Koza, R. A., & Kozak, L. P. (2005). Transcriptional synergy and the regulation Of Ucp1 during Brown Adipocyte induction in white Fat depots. Molecular and Cellular Biology, 25(18), 8311-8322. doi:10.1128/mcb.25.18.8311-8322.2005] 7000 1 r = 0.71 6000 5000 4000 Ucp1 3000 2000- 1000 0 250 500 750 1000 1250 1500 1750 PPAR alpha mRNA levels O A) As the Ucp1 level goes up, the PPAR alpha mRNA levels also increases by 0.71.Question 4 (1 point) If we use a recently developed equation/model for estimating percent body fat, as based on BMI (body mass index) and correlate this with the traditional BMI, we find a positive correlation. Suppose the overall correlation coefficient for both men and women is found to be 0.74. What then would be the correlation coefficient for these two variables forjust women? 0 A) The correlation coefficient must be the same for women as for the overall sample (r = 0.74) O B) We cannot determine the value based on this information 0 C) The correlation coefficient for women will be greater than for the overall sample 0 D) The correlation coefficient for women will be less than for the overall sample 0 E) If the sample is made equally of men and women, the correlation coefficient will be cut in half (r = 0.37) Previous Page Next Page Page 4 0f 11 7000 r = 0.71 6000 5000 4000 Ucp1 3000 2000 1000- 0 250 500 750 1000 1250 1500 1750 O PPAR alpha mRNA levels ( A) As the Ucp1 level goes up, the PPAR alpha mRNA levels also increases by 0.71. O B) An increase in PPAR alpha mRNA levels causes the Ucp1 levels to increase. O C) An increase in Ucp1 levels causes the PPAR alpha mRNA levels to increase. (D) There is an associated rise PPAR alpha mRNA levels per increase in the Ucp1 levels. O E) The graph is inconclusive since there are too many outliers present