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Question 9 (1 point) Pharmacokinetics is the study of movement of drugs in the body. One useful measure of pharmacokinetics is the maximum concentration (CMAX).

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Question 9 (1 point) Pharmacokinetics is the study of movement of drugs in the body. One useful measure of pharmacokinetics is the maximum concentration (CMAX). Maximum concentration provides information on the peak concentration of a drug in the blood after it has been administered. A pharmacokinetic study conducted on intravenous infusion of Acetaminophen among healthy patients up to the age of 60 measured the pharmacokinetics parameters for children, adolescents and adults. The study revealed a mean Acetaminophen CMAX for children of 27 mg/ml and a standard deviation to be 7 mg/ml. Suppose the CMAX for children who participated in the study is normally distributed. [Source: OFIRMEV (Acetaminophen) Retrieved from https://www.rxlist.com/ofirmev-drug.htm#description] What is the probability that the CMAX of one child is below 25 mg/ml? O O A) 0.3298 ( B) 0.7157 O O C) 0.6141 ( D) 0.2843 (E) 0.3859Question 10 (1 point) Most people think normal body temperature is 98.6 F. In 1992, the Journal of the American Medical Associationasserted that a more accurate figure may be 98.2 F on average, and that body temperatures had a standard deviation of 0.7 F. Assuming this is true and body temperatures follow a normal distribution, what is the probability that a body temperature will be above 99 OF? [Source: Mackowiak, P. A., Wasserman, S. S., & Levine, M. M. (1992). A critical appraisal of 98.6 degrees F, the upper limit of the normal body temperature, and other legacies of Carl Reinhold August Wunderlich. JAMA, 268(12), 1578- 1580.] ( A) 0.8729 O B) 0.2843 O C) 0.1271 O D) 0.7157 O E) 0.5714 Previous Page Next Page Page 10 of 11Question 11 (1 point) Which of the following statements is/are true about the normal distribution? |. The distribution is bimodal, with the modes of :1 standard deviation. ||. Because it is symmetric around the mean, 50% of the data are less than or equal to the mean, and the remaining 50% are above the mean value. 0 Statement | only 0 I need to see the distribution first before answering this. 0 Statement || only 0 Statement | and II only O Neither of the two statements us Page Next Page Page 11 of 11

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