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Question: A recent CT scan of lung of a new patient in Monument hospital detects a square size (4cm4cm) neoplastic formation. When examined in higher
Question: A recent CT scan of lung of a new patient in Monument hospital detects a square size (4cm4cm) neoplastic formation. When examined in higher magnification is was found that the tumor tissue is composed of cells with a diameter of 16m and perfectly packed in the tumor tissue. Using molecular antibodies they determined that each cell has 100,000 spherical shape receptor per cell and each receptor is 4nm in diameter. Please answer the following questions A) How many cells are there in the neoplastic lung tissue of this patient? B) calculate the fraction of the receptor occupied surface of these cells as opposed to phospholipid bilayer C) The cancer cells in this tissue was found to be induced by the presence of transforming growth factor (TGF) with a KD of 10M. The biochemical tests within the periphery of the tumor tissue found that there were 1M of TGF in the extracellular space of the tumor tissue within 1cm proximity of the tumor tissue. Based on this information, what proportion of the TGF will be bound to tumor cell receptors
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