Questions

1.One of the most significant shortcomings of the common law that led to the development of equity was inadequate remedies. As a result, many would be plaintiffs were left out; however, equity increased the remedies. With reference to the above statements discuss five equitable remedies.

2.What is the best time of day to administer omeprazole, and why?

3.Is it safe to use the drugs omeprazole and ranitidine during pregnancy?

4.Are non-steroidal anti-inflammatory drugs harmful to the stomach when

taken parenterally, for example by intravenous or intramuscular routes?

5.Is it safe to give a patient with a past history of bleeding peptic ulcer

aspirin in an antiplatelet dose of 75-325 mg?

6.Is sulpiride effective in the treatment of a peptic ulcer or gastrooesophageal reflux disease (GORD)?

7.Is clopidogrel gentle on the stomach?

8.Is there a drug interaction between non-steroidal anti-inflammatory

drugs (NSAIDs) and proton pump inhibitors (PPIs)?

9.Do antacids enhance mucosal resistance in the gastric mucosa? If so,

please indicate the mechanism.

10.Is there a drug interaction between antacids and H2-receptor blockers?

11.Does the combination of aluminium and magnesium hydroxide, given

as an antacid, decrease the absorption of omeprazole if these are

co-administered to help relieve heartburn quickly?

12.Should proton pump inhibitors be used with caution in patients with

renal impairment?

13.Has cisapride been withdrawn from the market because of the danger of

ventricular fibrillation?

14.In peptic ulcer disease:

1. What are the indications for an upper gastrointestinal endoscopy?

2. As this is an invasive procedure, is an oesophagogastroduodenoscopy

(OGD) or barium meal X-ray preferable?

15.Is telithromycin as, or more, effective than clarithromycin in the

treatment of Helicobacter pylori? If so, what is the recommended dosage

and how long should treatment be continued?