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Regarding the test for orthogonal regression: There are measuring devices A and B . There are three types of samples: a , b , and

Regarding the test for orthogonal regression:
There are measuring devices A and B.
There are three types of samples: a, b, and c.
Sample a is measured 5 times with measuring device A, and similarly, sample a is measured 5 times with measuring device B.
Aa: Aa1, Aa2, Aa3, Aa4, Aa5
Ba: Ba1, Ba2, Ba3, Ba4, Ba5
Likewise, the other samples b and c are each measured 5 times with their respective measuring devices.
Ab: Ab1, Ab2, Ab3, Ab4, Ab5
Bb: Bb1, Bb2, Bb3, Bb4, Bb5
Ac: Ac1, Ac2, Ac3, Ac4, Ac5
Bc: Bc1, Bc2, Bc3, Bc4, Bc5
I want to use these measurements to conduct a test using orthogonal regression to determine if the outputs from measuring devices A and B are the same. The software used for the test will be Minitab.
During this test, the mean values of Aa, Ab, Ac, Ba, Bb, and Bc (for example, Aa =(Aa1+Aa2+Aa3+Aa4+Aa5)/5) are calculated. I would like to know if there will be a difference in results between testing for orthogonal regression using the mean values of these three sets and using all 15 individual values from measuring devices A (Aa1, Aa2, Aa3, Aa4, Aa5, Ab1, Ab2, Ab3, Ab4, Ab5, Ac1, Ac2, Ac3, Ac4, Ac5) and B (Ba1, Ba2, Ba3, Ba4, Ba5, Bb1, Bb2, Bb3, Bb4, Bb5, Bc1, Bc2, Bc3, Bc4, Bc5). What kind of differences in results might occur? Which method is correct for testing whether measuring devices A and B produce the same values?

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