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RIFAMPICIN IS A SEMI SYNTHETIC ANTIBIOTIC USED IN THE TREATMENT OF TB. RIFAMPICIN HAS AN ELIMINATION HALF RATE OF 2.8.HR. ABSORPTION RATE CONSTANT 0.7 AND

RIFAMPICIN IS A SEMI SYNTHETIC ANTIBIOTIC USED IN THE TREATMENT OF TB. RIFAMPICIN HAS AN ELIMINATION HALF RATE OF 2.8.HR. ABSORPTION RATE CONSTANT 0.7 AND VOLUME OF DISTRIBUTION IS 0.65L/KG. WOMEN WEIGH 70KG IS TO BE TREATED FOR TB 450 MG RIFAMPICING GIVEN IV OVER TWO HOURS TWICE A DAY. IS THE DOSING REGIMEN SAFE AND EFFECTIVE IF THERAPEUTIC WINGWO IS BETWEEN 0.5-10MG/L

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