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Scaling up a microfluidic reactor design for continuous production of a pharmaceutical intermediate presents several challenges. One key concern is maintaining efficient mixing within the

Scaling up a microfluidic reactor design for continuous production of a pharmaceutical intermediate presents several challenges. One key concern is maintaining efficient mixing within the reactor on a much larger scale.


Traditional stirred-tank reactors rely on impellers to create turbulent flow, but these may not be suitable for the high surface area-to-volume ratio characteristic of microfluidic channels.


Propose two alternative strategies, along with their advantages and disadvantages, for achieving efficient mixing in a scaled-up version of this microfluidic reactor for continuous production.

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