Section 4.5 - The Substitution Rule Concept Questions 1. State the Substitution Rule. 2. How is integration by substitution related to the Chain Rule? Problem with Explanation Solve the following problem. Include an explanation so that a peer in the class can understand the work. Your explanation should have an emphasis on explaining calculus concepts over algebraic concepts. Reminder: this take-home assessment is due on December 13, 2021. Problem Prompt: Evaluate the indefinite integrals. 1. (sec @ tan #) v1 + sec 0 de 2. cos 0 . sin (sine) de 3. 1v5 - r dr