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Simone was hypoxemic (i.e., she had a decreased Pao 2 ). However, she was not hypercapnic (i.e., she did not have CO 2 retention or

Simone was hypoxemic (i.e., she had a decreased Pao2). However, she was not hypercapnic (i.e., she did not have CO2 retention or an increased Paco2). In fact, at 37 mm Hg, her Paco2 was slightly lower than normal. Simone clearly has a problem with O2 exchange, but she does not seem to have a problem with CO2 exchange. How can hypoxemia occur in the absence of hypercapnia?

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