Question
single IV bolus injection concentration containing 500 mg of cefamandole nafate (Mandol, Lilly) is given to an adult female patient (63 years, 55kg) for
single IV bolus injection concentration containing 500 mg of cefamandole nafate (Mandol, Lilly) is given to an adult female patient (63 years, 55kg) for a septicemic infection. The apparent VD is 0.1 L/Kg and the elimination half-life is 0.75 hours. Assuming the drug is eliminated by first-order kinetics and may be described by a one-compartment model: What is the amount (mg) of drug in the body 4 hours after the dose is given?
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Chemistry The Central Science
Authors: Theodore Brown, Eugene LeMay, Bruce Bursten, Catherine Murphy, Patrick Woodward
12th edition
321696727, 978-0132175081, 978-0321696724
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