Question
The solution of Propranolol Hydrochloride (Mr = 295.8 g mol^-1) with a concentration of 1.80 g/L was prepared. Predict the theoretical pH of precipitation for
The solution of Propranolol Hydrochloride (Mr = 295.8 g mol^-1) with a concentration of 1.80 g/L was prepared. Predict the theoretical pH of precipitation for this solution.
Measurement | Record |
the pH of drug solution | 3.9 |
The initial volume of NaOH (mL) | 2.10 |
The final volume of NaOH (mL) | 3.50 |
The total volume of NaOH used (mL) | 1.40 |
pH at precipitation | 8.4 |
The initial volume of HCl (mL) | 2.70 |
The final volume of HCl (mL) | 3.35 |
The total volume of HCl used (mL) | 0.65 |
Appearance after adding water | Cloudy |
Pka of propranolol = 9.50
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Organic Chemistry
Authors: L. G. Wade Jr.
8th edition
321768418, 978-0321768414
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