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Stutter Stopper? Drug for Stutterers Shows Promise: Indevus Says Pill Reduced Incidents for Most in 1st Trial Author: Stephen Heuser Source: Boston Globe, May 25,

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Stutter Stopper? Drug for Stutterers Shows Promise: Indevus Says Pill Reduced Incidents for Most in 1st Trial Author: Stephen Heuser Source: Boston Globe, May 25, 2006, http://archive.boston.com/business/globe/articles/2006/05/25/drug_for_stutterers_shows_pron The following is an extract from a Boston Globe article on stuttering: A potential pill to treat stuttering took a step forward yesterday when Indevus Pharmaceuticals Inc. of Lexington said its experimental drug reduced stuttering in a majority of patients in its first clinical trial. The 132-patient trial is the largest human test ever conducted on a drug for stuttering, according to the company. The Indevus drug, called pagoclone, was given to 88 patients in escalating doses, with the rest of the trial subjects receiving a placebo. The patients were then tracked using several widely accepted measures of stuttering. On a third rating scale, based on doctors' impressions, the pagoclone patients scored a "numerically superior rating" to the placebo group, but the finding did not reach statistical significance. Question: What is the null hypothesis that is being tested? 88 out of 132 patients who take Pagoclone will experience improvements with their stuttering symptoms. Pagoclone is no better at improving stuttering symptoms than a placebo is. Pagoclone is no better at improving stuttering symptoms than Indevus. Pagoclone is better at improving stuttering symptoms than a placebo is

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