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Suggest reagents that would accomplish each of the steps (a) and (d). (2 marks) Demonstrate your understanding of retrosynthetic analysis by redrawing step (b) in
- Suggest reagents that would accomplish each of the steps (a) and (d). (2 marks)
- Demonstrate your understanding of retrosynthetic analysis by redrawing step (b) in the retrosynthetic direction to show the disconnection of compound 2 and the synthons that correspond to the two reagents. (2 marks)
- Propose a mechanism for the Swern Oxidation, step (c). (5 marks)
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OH b. EtMgBr, THF . HO. BnO. BnO, H. H. 1 c. DMSO, (COCI)2, Et3N OTES d. BnO, BnO. 3 Et = ethyl (-CH2CH3); Bn = benzyl (-CH2PH); TES = triethylsilyl (-Si(CH2CH3)3) %D TBS = tert-butyldimethylsilyl (-Si((CH3)2C(CH3)3)); DMSO = dimethylsulfoxide %3! 2.
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