Survival in cohort 1.0 - groups (P$0.0 COVID-19, D- Survival probability 0.8- dimer is an activ have shown that 0.6 - in patients with a marker of mo 0.4 - gency departme 0.2 - [19]. In recent in the death g 0.0 - Log rank P = 0.031 vated levels of 20 40 60 RO for death of ad Time (days) We found that of D-dimer at No. of at risk Nondiabetic: 123 120 are significantly 102 63 Diabetic: 76 67 56 ment with low to odds of d Nondiabetic COVID-19 inf Diabetic injury and the FIGURE 1: Survival curve in patients with COVID-19 pneumonia clinical trials with and without diabetes. the application Currently, cause of high n hetes, DiabetesJournal of Diabetm Research TABLE 1: Bowline characterlaties of patients with COVID. 19 pneumonia admission to hospital No. (4) Total Diabetic Nondiabetic In = 199) App, median [IRL years 63 130-79) 67 (61-781 Female 110 (35 5) 37 (48 7) 0.142 Male Symptoms Fever 148 (34.4) 94 (76.41 Cough 133 (66 8) 54 (71.4) 79 464.2 0.920 Dyspnea 53 (26.6) 23 (289) 31 (35.2) 0.552 50 (35.1) 16 (21.1) 34 437.6) 0.289 Anorexia 32 (16.1) (LLa) 23 (187) Nausea 5 (6.6) 18 (14.5) 0.084 Headache 10 (10.1) 5 (65) 15 (127) Diarrhea 6 (30) 5( 40) 0.410 Vomiting 3(3 3) 0.651 Darrinca 2 (1.0) 20.599 Onset of initial symptoms to hospital admission (days), (IQR] 10 46-151 10 (3-14) 12 (7-20) Duration of hospital stay (day), (NR) 13 18-20) 13 (9-19) 12 (7-21) 0.908 CHnical outcome Died 18 (90) II (145) 7 (57) 0 036 Alive 181 1910) 116194 31 COVID-14 accamirandoran 1019, HOR: Interquire ranger nor nombeer. 2.2. Definitions. COVID-19 was confirmed by detecting SARS- 3. Results COV-2 RNA in throat swab samples using a virus nucleic acid detection kit according to the manufacturer's protocol 3.1. Baseline Characteristics. 199 patients with COVID-19 (Shanghai BloGerm Medical Biotechnology Co, Led). All of pneumonia were included in our study (Table 1). Among patients were admitted to the general fever ward excluding them, 76 were diabetic and 123 were nondiabetic, The the Intensive care unit. The cases were divided into diabetic median age of patients with COVID-19 pneumonia with dis and nondiabetle groups according to the history of taking anti- beles was 67 years (1QR: 61-78), which was significantly diabetic drugs or by plasma fasting blood glucose level at higher than that of patients without diabetes (IQR: 47-68, admision P 0.001). The onset of initial symptom to hospital admis sion in patients with diabetes group was 10 days (IQR 5-14), while patients without diabetes group was 12 daysJournal of Diabetes Research TABLE 2: Laboratory findings of patients with COVID.19 at admission Normal range "Tool (n = 199) Modlin (108] White blood cell court. * 10*/1. Diabetic (n = 76) Nondubelic (nie 123] Lymphocyte cant, * 1071. 37-10 5.6 (4.1-7.0) 0.60-4.00 5.3 (41-6.5) Prothrombin time, s 1 17 (0.50-1.61) 1 1 1 (073-142) 1.19 40.54-1173) 0.036. 9-13 Activated partial thromboplastin time, s 122 (115-13.3) 123 (11.7-13.4) 0.430 20-40 12.2 (11.4-13.1) D-dimer, mg/L 261 (325-31.0) 25 8 (210-10.1) 26 7 (23-31 6) 0.105 Total bilirubin, mmol/L 0-055 0.62 (0.33.1.68) 0.96 (054-2.89) 050 10.36-1 32) 40 001 2-25 Albumin,/L 8.4 (59-132) 98 (70-146) 75 (3.8-12.3) 0.040 35 55 36 5 (33.5-402) 35.2 (31.9-353) 37.7 (34.7 407) 0.002 Blood urea nitrogen, mmoll 2.6-75 43 (3-65) 4.9 (35.7.3) 4.3 (3.3.5.5) 0.022 Creatinine. pmol/L 41-73 69.3 (55.1-83.5) 20.7 (55.3-8401 685 (55.1-63.5) Scrum potassium J.5-5.5 3.77 (5.40-4 10) 375 (3.40-4.1.)] 3.77 (3.44-4.09) 0.547 Farting plasma plusone 36-611 5.93 (5.00 7.50) 792 (654-1019) 537(4.94-5.93) Omggen saturation 97% 195-98%7 COVID-19, coronavirus disease 2019. 10P. interquartile range, co, number. TANER J: Mekhivariate analysis of Independent risk factors associated with in-hospital death. Variables P vile OR (93% CD) 1 026 (0 969.1.087) Cardiovascular disease (yes verpas no) 0.250 (0.020-3.155) Chronic kidney disease (yes venus no) 0.083 8.934 (0.752:106.073) Hypertension (yes versus ro) 0.650 (0.150-2908) Diabetes (yes verui no) 2007 10816 (1.895-61.741) D-dimer at admission, my/L. 1.094 (1 017-1.178) Lymphocyte count at admission (