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Table 4.8 shows results of an eight-center clinical trial to compare a drug to placebo for curing an infection. At each center, subjects were randomly

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Table 4.8 shows results of an eight-center clinical trial to compare a drug to placebo for curing an infection. At each center, subjects were randomly assigned to treatments.Analyze these data, available in the Infection data file at the text website. Using logistic regression, describe and make inference about the treatment effect.

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Table 4.8 Clinical trial data for Exercise 4.14. Response Response Center Treatment Success Failure Center Treatment Success Failure 1 Drug 11 25 5 Drug 6 1 1 control 10 27 control 0 12 2 Drug 16 4 6 Drug 1 10 control 22 10 control 0 10 3 Drug 14 5 7 Drug 1 4 control 7 1 2 control 1 8 4 Drug 2 14 8 Drug 4 2 control 1 1 6 control 6 1 Source: P.J. Beitler and LR. Landis, Biometrics, vol. 41, pp. 9911000 {1985).

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