TABLE: 6-1 Dx Checklist Major Depressive Episode 1. For a 2-week period, person displays an increase in depressed mood for the majority of each day and/or a decrease in enjoyment or interest across most activities for the majority of each day. 2. For the same 2 weeks, person also experiences at least 3 or 4 of the following symptoms: Considerable weight change or appetite change Daily insomnia or hypersomnia Daily agitation or decrease in motor activity Daily fatigue or lethargy Daily feelings of worthlessness or excessive guilt Daily reduction in concentration or decisiveness Repeated focus on death or suicide, a suicide plan, or a suicide attempt. 3. Significant distress or impairment. Major Depressive Disorder 1. Presence of a major depressive episode 2. No pattern of mania or hypomania Persistent Depressive Disorder 1. Person experiences the symptoms of major or mild depression for at least 2 years. 2. During the 2-year period, symptoms not absent for more than 2 months at a time. 3. No history of mania or hypomania. 4. Significant distress or impairment.