Task 1. 1.3-year old child is diagnosed with hemophilia. Which hemostasis (primary or secondary) is affected in this diseases and which hemostasis tests will appear to be positive? Task 2. Which test is used to differentiate rash elements of hemorrhagic origin from rash elements of non hemorrhagic inflammatory origin

1. List all indexes in CBC used for red blood cells examination.

What are its normal levels?

2. A 14 year old girl reveals to have a general malaise, weakness (difficulty picking up or

carrying her school bag), getting easily tired and out of breath, especially during physical

activity; Her mother is concerned that the girl is very pale; has stopped eating meat^ eggs

and fish, and for the past month it seems that she barely eats trying to decrease her weight.

The girl mentioned that she also has an urge to eat raw potatoes and can't get enough of

the smell of nail polish. Patient history revealed that about half a year ago her first period

started since then her menstruations were irregular, lengthy, and bloody. She has

consulted recently with a children's gynecologist. During examination the following was

noted: the girl is of normal physical development. Skin and mucus membranes are visibly

pale; while her sclera seem somewhat bluish. Her taungue is reddish, a bit swollen, and

sleek. Cardiopulmonary examination revealed a functional systolic murmur most

pronounced at the apex. Abdomen is not enlarged; it is soft and painless in superficial and

deep palpation. Liver is +0,5 cm below the costal arc. Spleen isn't enlarged. Laboratory

data: RBC - 3.0x10 12 /L, Hb - 75 g/L, CI - 0.75, RTC 20 , Plt - 200 x10 9 /L; WBC

6.5x10 9 /L, B - 1%, E - 1%, N - 63%, L - 28%, M - 7%; ESR - 13 mm/h. Erythrocyte

morphology displays microcytosis, anisocytosis, poikilocytosis.

List all pathological signs present in this task. Give an interpretation to results of lab

testing.

3. Compose complete blood count typical for iron deficiency anemia.