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The antiviral drug Acyclovir has an elimination half-life (t1/2,elim) of 2.5 hr and a volume of distribution (V) of 0.8 L/Kg. Estimate the following information
The antiviral drug Acyclovir has an elimination half-life (t1/2,elim) of 2.5 hr and a volume of distribution (V) of 0.8 L/Kg. Estimate the following information for a 70 Kg patient that receives a dose of iv injection of 10 mg/kg of Acyclovir.
(a) The elimination rate constant (k) of Acyclovir?
(b) The plasma concentration of the Acyclovir 4 hr after injection?
(c) The amount (not concentration) of Acyclovir remaining in the patient 6 hr after injection?
(d) The time it will take for 99% of Acyclovir to be eliminated?
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