The book describes the polymerase chain reaction. A) If one of the primers has a point mutation distinct from the template what is the percentage of double- stranded DNA that contains a single point mutation after 3 PCR cycles (melt-anneal-polymerize)? B) Illustrate where you would place primers, and in what orientation, to amplify circular double-stranded DNA (arrows along strands to indicate 5' 3' direction)? Note this necessarily creates linear DNA. Is the DNA amplification linear or exponential?