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The drug risperidone (Figure 1) is used to treat bipolar disorder, irritability in people suffering with autism and schizophrenia. Figure 1. Risperidone. a) Using the

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The drug risperidone (Figure 1) is used to treat bipolar disorder, irritability in people suffering with autism and schizophrenia. Figure 1. Risperidone. a) Using the equation given below (Figure 2), calculate the Andrew's Binding Energy for risperidone. Does your answer indicate that risperidone is likely to bind well to its receptor? ( 60% of marks) Gtinding=14(0.7DOF)+(0.75p2)+(0.85p3)+(11.5N+)+(1.2Nneutral) +(8.2CO2)+(10PO4)+(2.5OH)+(3.4C=O)+(1.1O/S)+(1.3 hal ) Figure 2: Equation for calculation of Andrew's Binding Energy b) Using the answer from part a, does Andrew's Binding Energy predict risperidone has an intrinsic ability to bind to its receptor? Explain your answer. The drug risperidone (Figure 1) is used to treat bipolar disorder, irritability in people suffering with autism and schizophrenia. Figure 1. Risperidone. a) Using the equation given below (Figure 2), calculate the Andrew's Binding Energy for risperidone. Does your answer indicate that risperidone is likely to bind well to its receptor? ( 60% of marks) Gtinding=14(0.7DOF)+(0.75p2)+(0.85p3)+(11.5N+)+(1.2Nneutral) +(8.2CO2)+(10PO4)+(2.5OH)+(3.4C=O)+(1.1O/S)+(1.3 hal ) Figure 2: Equation for calculation of Andrew's Binding Energy b) Using the answer from part a, does Andrew's Binding Energy predict risperidone has an intrinsic ability to bind to its receptor? Explain your

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