The Embassy of Canada in Argentina manages the Canada Fund for Local Initiatives, which provides financial assistance to fund modestscale projects. Since 2007, Canada has supported projects in Argentina related to climate change and sustainable development, gender and human rights, among others. As well, the International Development Research Centre supports research in Argentina to promote growth and development. Argentine researchers are focusing on issues such as labour markets, female and youth employment, Mercosur trade and integration issues, alternatives to tobacco farming, and the country's efforts to help strengthen democracy and rebuild in Haiti. 35 In upper gastrointestinal bleeding, without knowing the cause or source of bleeding, why do we give proton pump inhibitors (PPIs, e.g. omeprazole)? What is the role of these, if the source of bleeding is not peptic or duodenal ulcer? 36 Why is the incidence of coeliac disease increasing in many countries? 37 Are small amounts of gluten harmful to a patient with coeliac disease? 38 I refer to the treatment of complications related to diverticular disease. Under 'bleeding' you mention that 'Persistent bleeding can often be arrested by undertaking an "instant" barium enema, which acts to plug the offending diverticulum'. When I mentioned this to my consultant he said he had never heard of this. Could you clarify how this would work and where I could obtain more information? 39 In children with abdominal pain and fever, does a white cell count help establish a diagnosis of appendicitis? 40 I have always been taught that ulcerative colitis only affects the large bowel with some associated proctitis. I read in your chapter on gastrointestinal disease that it can cause mouth ulcers and am now confused. 41 In pseudomembranous colitis, what is the first treatment of choice, metronidazole or vancomycin? 42 Is Crohn's disease considered as an autoimmune disease. If it is, are there other predisposing factors to it other than genetics? If it is not, what is its nature? 43 Why does carcinoma of the ascending colon cause more anaemia than obstruction, and carcinoma of the descending colon more obstruction features and less anaemia?