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The following compound has very poor bioavailability. Why does this compound have poor bioavailability and how would you improve the bioavailability using bioisostere replacement. Explain

The following compound has very poor bioavailability. Why does this

compound have poor bioavailability and how would you improve the

bioavailability using bioisostere replacement. Explain why your new

compound would have enhanced bioavailability.

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