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The following data correspond to one marker taken from a genome-wide association study (GWAS) of genetic variants related to heart disease. The number of individuals

The following data correspond to one marker taken from a genome-wide association study (GWAS) of genetic variants related to heart disease. The number of individuals are categorized by case-control status, as well as their genotype at this marker (AA, AG, or GG).

AAAGGG

Cases

(heart disease)

3157021410

Controls

(no heart disease)

857231717

What would you conclude based on these data?

Group of answer choices

a. This marker is likely to be closely linked to a gene that affects heart disease risk, and the A allele is associated with higher disease risk.

b. This marker is likely to be closely linked to a gene that affects heart disease risk, and the G allele is associated with higher disease risk.

c. This marker is not likely to be closely linked to a gene that affects breast cancer risk.

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