Question
The following data correspond to one marker taken from a genome-wide association study (GWAS) of genetic variants related to heart disease. The number of individuals
The following data correspond to one marker taken from a genome-wide association study (GWAS) of genetic variants related to heart disease. The number of individuals are categorized by case-control status, as well as their genotype at this marker (AA, AG, or GG).
AA | AG | GG | |
Cases (heart disease) | 315 | 702 | 1410 |
Controls (no heart disease) | 85 | 723 | 1717 |
What would you conclude based on these data?
Group of answer choices
a. This marker is likely to be closely linked to a gene that affects heart disease risk, and the A allele is associated with higher disease risk.
b. This marker is likely to be closely linked to a gene that affects heart disease risk, and the G allele is associated with higher disease risk.
c. This marker is not likely to be closely linked to a gene that affects breast cancer risk.
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Introductory Statistics
Authors: Prem S. Mann
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9781118473986, 470904100, 1118473981, 978-0470904107
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