The following data were taken from a study of 1000 expectant mothers. The expectant mothers were given questionnaires about their prenatal care, including whether or not they took folate supplements throughout their pregnancy. After birth, the infants were evaluated for neural tube defects (NTDs; birth defects of the brain, spine, or spinal cord), the following results:

Group	No NTD	Yes NTD
Took folate	471	4
No folate	498	27

1. Use ac² testto determine if there is a difference in development of NTDs between the folate and no-folate populations.
2. If there is a difference, quantify the degree of association between the mother's not supplementing with folate and the development of NTD(s) in the infant. Provide your result in a single complete sentence that would convey your conclusion in a way that could be understood by a non-expert in statistics or medicine (e.g., a typical reader of a local newspaper).