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The following plasma concentration versus time profile was obtained after a single dose of Koemycin (an experimental drug). What is the rate constant for Koemycin

The following plasma concentration versus time profile was obtained after a single dose of Koemycin (an experimental drug). What is the rate constant for Koemycin?

Time (hr)

Drug conc. (mg/L)

2

100.0

6

62.5

8

50.0

14

25.0

20

12.5

26

6.25

0.116 (rate unit)

0.226 (rate unit)

0.336 (rate unit)

0.446 (rate unit)

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