Question
The formulation design of suspension dosage forms demand a clear comprehension of micromeritics, surface chemistry and rheological behavior of heterogeneous systems. Based on this understanding,
The formulation design of suspension dosage forms demand a clear comprehension of micromeritics, surface chemistry and rheological behavior of heterogeneous systems. Based on this understanding, please answer questions a through c.
a)Explain the formation of an Electric Double Layer in a liquid suspension and how this influences the overall dispersibility of insoluble drug particles in the system.
b)Briefly describe three (3) Electrokinetic Phenomena that are possibly produced due to the interfacial potential in such systems.
c)A four (4) fluid ounce suspension formulation on stability exhibits a sedimentation rate of 2ml/month. Assuming that the companys acceptable sedimentation volume is 0.4 mL, what is the predicted shelf-life of this product?
Step by Step Solution
There are 3 Steps involved in it
Step: 1
Get Instant Access to Expert-Tailored Solutions
See step-by-step solutions with expert insights and AI powered tools for academic success
Step: 2
Step: 3
Ace Your Homework with AI
Get the answers you need in no time with our AI-driven, step-by-step assistance
Get Started