the manufacture of pharmaceuticals, most active pharmaceutical ingredients (APIs) are made in solution and then recovered by separation. Acetaminophen, a pain killing drug commercially marketed as Tylenol, is synthesized in an aqueous solution and subsequently crystallized. The slurry of crystals is sent to a centrifuge from which two effluent streams emerge: (1) a wet cake containing 85.0 wt% solid acetaminophen (MW = 151 g/mol) and 15.0 wt% water (plus some acetaminophen and other dissolved substances, which we will neglect), and (2) a highly dilute aqueous solution of acetaminophen that is discharged from the process. The wet cake is fed to a dryer where the water is completely evaporated, leaving the residual acetaminophen solids bone dry. If the evaporated water were condensed, its volumetric flow rate would be 55.0 L/h. Following is a flowchart of the process, which runs 24 h/day, 315 days/yr. A denotes acetaminophen. A in Solution To Waste Disposal Aqueous Slurry of A(s) CENTRIFUGE L HOC)/ Wet Cake WA wt% A(S) ww wt% H2O DRYER me tonne A(s)/yr WA = 85.0 Ww= 15.0 F = 55.0 LH2O(1) /h Calculate the yearly production rate of solid acetaminophen (tonne/yr), using as few dimensional equations as possible. o tonne/yr Adapted from Stephanie Farrell, Mariano J. Savelski, and C. Stewart Slater (2010), "Integrating Pharmaceutical Concepts into Introductory Chemical Engineering Courcor Dart http://pharmabubarrocourer 1200