The overall control, performance evaluation and incentive system improved CHNG's managing style and system for the whole group. CHNG's inner management system is established on the basis of investment capital control. The evaluation results are the basis of exercising the shareholders' rights of making decisions, selecting managers, and enjoying the earnings. The set of evaluating criteria is to standardize the entire companies' behaviors. In order to make evaluating criteria better reflect the subsidiary companies' operating conditions, CHNG's top management also decided to standardize and improve all subsidiary companies' financial management and assets management. For example, Equity Method is used in its long-term investments; interest payable is recorded as Financial Expenses; estimated or unrealized gains or losses should not be included in a subsidiary company's Income Statement as realized profits or losses; and bad debt expenses must be recognized.

111 Is the use of amlodipine or furosemide recommended to normalize blood pressure in a case of hypertensive heart failure? If so, which is most effective?

112 How can diabetes cause endothelial dysfunction? What are the roles of ACE inhibitors in the kinin-kallikrein system? What are the mechanisms by which a decrease in the level of nitric oxide causes endothelial dysfunction?

113 Can sublingual nifedipine be given to a patient with malignant hypertension/accelerated hypertension? It seems to be a controversial issue with some favouring it and some against it.

114 Is the diagnosis of malignant hypertension based only on the basis of the retinopathy (even in the presence of a normotensive state)? Labetalol, parenterally, is suggested as a treatment for malignant hypertension. What other more readily available preparations (besides sodium nitroprusside) are recommended in addition to this drug? Parental labetalol is not available in Pakistan!

115 Patients at medium risk of DVT and pulmonary embolism are usually given specific prophylaxis with low-dose heparin at a dose of 5000 units subcutaneously every 8-12 hours until the patient is ambulatory. Is the first dose given immediately after, say, extensive varicose vein surgery of small and great saphenous veins?

116 'Anticoagulants are not necessary, as embolism does not occur from superficial thrombophlebitis' (K&C 7e, p. 809). Why?

117 Can we use enoxaparin for deep vein thrombosis (DVT) prophylaxis in the immediate postoperative period and in a case of cerebral haemorrhage? Wouldn't it increase the risk of haemorrhage in either case?

118 Can external jugular vein thrombosis cause tingling numbness over the earlobe and adjoining part of the lower face?

119 For how long does a patient have to stay in bed to be labelled as bedridden and to merit low-molecular-weight heparin (LMWH) as prophylaxis for deep vein thrombosis?

120 Is an inferior vena cava filter an alternative treatment for a patient with a history of recurrent deep vein thrombosis on lifelong anticoagulation with warfarin?