Question
The pk parameters for a drug given intravenously were described in the equation: D B = 1000 e -0.17 t (amount in mg, time in
The pk parameters for a drug given intravenously were described in the equation: DB = 1000 e-0.17 t (amount in mg, time in hour) and plasma concentration after 6 hours was found to be 14.4 mg / L.
Calculate:
A. The elimination half-life
B. The initial concentration
C. The apparent volume of distribution
D. The total body clearance
E. The Area Under the Curve
F. The percent amount eliminated after 12 hours.
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a The Elimination halflife k0693t 12 0170693t12 t124076hrs b The initial concentration CCoe ket 144...Get Instant Access to Expert-Tailored Solutions
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