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The results of a randomisedcontrolled trial failed to show a statistically significant effect of the intervention compared to placebo. The trial was well-conducted and well-designed
The results of a randomisedcontrolled trial failed to show a statistically significant effect of the intervention compared to placebo. The trial was well-conducted and well-designed with a recruitment target based on a sample size estimation done in advance.
What should we conclude about the null hypothesis of no difference between the groups in the primary outcome?
- The null hypothesis is false (this trial result was a Type II error)
- The null hypothesis is true (the intervention does not work)
- We don't know if the null hypothesis is true or if this trial result was a Type II error
- You should do a post-hoc power calculation to confirm that the null hypothesis is true
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