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This is a figure from the Ramirez et al. experiment. article link below: https://pubmed.ncbi.nlm.nih.gov/23888038/ https://www.science.org/doi/pdf/10.1126/science.1239073?casa_token=z9GCZoCUiTAAAAAA:x8g2_DLTZg-I1YfSy6lwJ0NWf7jqFZa3qHv_rho2FiiA68uHSq-NkaHP7WQDhPXnAEfDFb0AjmDDgVc 1a) Use the principle of fire together, wire together to

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This is a figure from the Ramirez et al. experiment. article link below:

https://pubmed.ncbi.nlm.nih.gov/23888038/

https://www.science.org/doi/pdf/10.1126/science.1239073?casa_token=z9GCZoCUiTAAAAAA:x8g2_DLTZg-I1YfSy6lwJ0NWf7jqFZa3qHv_rho2FiiA68uHSq-NkaHP7WQDhPXnAEfDFb0AjmDDgVc

1a) Use the principle of "fire together, wire together" to explain why the red bar in A' is low. As part of your explanation, address:

- What is different about the red bar condition and the blue bar condition

- What neurons did or did not "fire together" to cause a memory to happen or not happen.

image text in transcribedimage text in transcribed
A C B C' A' Dox A +/- DG ChR2-mCherry, n = 11 mCherry, n = 12 ChR2-mCherry, No light, n = 9 40 30 Freezing (%) 20- 10 A C C' A'A C B C' A' Dox +/- DG ChR2-mCherry mCherry ChR2-mCherry, No light 40 30 Freezing (%) 20- 10- 0 A C C' A

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