Thus this will help to establish or improve understanding. Important question to ask when choosing the most suitable research design include whether a structured laboratory procedure, under which persons and/or groups involve assigned to an action or control arm, is ideal or even possible? Or if the desire is to get a more conceptual comprehension of a matter? Preferably, the latter is researched using a regulated study approach, whilst both of these can be studied more adequately using qualitative case study approach.

31 Do potassium channel activators such as nicorandil have any benefit in the treatment of a diabetic patient with cardiovascular complications?

32 Is a dosage of 2.5 mg/day of methyltestosterone, as a component in some multivitamin formulae, safe to give to diabetics or will it make the diabetes more difficult to control (see also Chapter 5, question 5)?

33 How does diabetes mellitus cause atherosclerosis?

34 How does diabetes cause renal damage, especially diabetic nephropathy with the presence of microalbuminuria?

35 Type 1 diabetes causes nephropathy in 40% of cases and type 2 causes it in 20% of cases but the most common cause of nephropathy we see is type 2, why?

36 Why is intractable vomiting seen in diabetes mellitus and how can it be managed?

37 Is gabapentin superior to carbamazepine in terms of efficacy in the treatment of painful diabetic neuropathy? What are its side-effects?

38 Why is diabetic ketoacidosis more common in type 1 diabetes?

39 Why is there abdominal pain in diabetic ketoacidosis?

40 Grades of ketonuria are sometimes mentioned. I have not been able to locate a detailed description in textbooks and would be grateful if you could explain the grades of ketonuria or recommend suitable reading material