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To calculate sensitivity, specificity, and predictive values of a test, which of the following is correct: It is necessary to know the truth about the

To calculate sensitivity, specificity, and predictive values of a test, which of the following is correct:

It is necessary to know the truth about the disease status of the people in the hypothetical population and the results of the test.
It is not necessary to know the truth about the disease status of the people in the hypothetical population because we can find it by subtracting the numbers in the test to the total number.
Only the truth about the disease status should be considered.
Only the true results of the test should be considered.

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