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2. Given the following biosynthesis scheme, answer the questions (a)-(c) below: OH O Me C E Me Me SACP OH OH A Me Me
2. Given the following biosynthesis scheme, answer the questions (a)-(c) below: OH O Me C E Me Me SACP OH OH A Me Me Me OH O SACP SACP D SACP Me B 4 OH Me Me Me SACP SACP (a) Determine the missing enzyme, or sequence of enzymes, involved in the steps A-E. The answers must include the name of the enzyme, or its two-letter abbreviation, together with any relevant co-factors involved with the individual enzymes. For the steps involving more than one enzyme, the correct order in which they are used must be clearly indicated. (b) Draw the structures of the two different enzyme bound substrates involved in steps B and i D, respectively. Abbreviations for the attached enzymes are acceptable (eg. ACP). (c) Draw the structures of the TWO biosynthetic intermediates formed during step C.
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